Lab of Developmental Genetics_Dr. Ming-Der Lin

Contact information
Ming-Der Lin, Ph. D.
Associate Professor
Department of Molecular Biology and Human Genetics
e-mail: mingder@gms.tcu.edu.tw
Lab website:
http://ls.tcu.edu.tw/mdlin/index.php
Orcid:
https://orcid.org/0000-0003-3411-5685

Google scholar: https://scholar.google.com.tw/citations?user=8zK3-LoAAAAJ&hl=zh-TW&oi=ao

Brief introduction of PI and the laboratory 

We adopt both zebrafish and Drosophila models to study the following topics:

  1. Investigation of the efficacy and mechanism of herbal drugs on treating glucocorticoid-induced osteoporosis
  2. Functional investigation of the disease-causing genes of human hereditary diseases
  3. Investigation of the role and function of genes responsible for developmental processes

Research Interests and 5 representative papers

  1. Cheng-Huan Peng, Wen-Ying Lin, Chia-Ying Li, Kameshwara Kumar Dharini, Chih-Yu Chang, Jo-Ting Hong, Ming-Der Lin* (2022, Jul). Gu Sui Bu (Drynaria fortunei Sm.) antagonizes glucocorticoid-induced mineralization reduction in zebrafish larvae by modulating the activity of osteoblasts and osteoclasts. Journal of Ethnopharmacology, (SCI, 4/30, INTEGRATIVE & COMPLEMENTARY MEDICINE).
  2. Rui-Yi Chen, Bui Thi Ngoc Hieu, Gilbert Audira, Bao Lou*, Ming-Der Lin*, and Chung-Der Hsiao* (2020, Jul). Meta-Transcriptomic Analysis of RNAseq Data Reveals Pacu and Loach Fish with Unusually High Levels of Myoglobin Expression in Skeletal Muscles. Animals, 10(7), 1130. (SCI, 19/146, Veterinary Sciences).
  3. Szu-Chieh Wang, Yung-Hao Ching, Preethi Krishnaraj, Guan-Yu Chen, Anna Shiny Radhakrishnan, Hsien-Min Lee, Wu-Chun Tu, and Ming-Der Lin* (2020, Feb). Oogenesis of Hematophagous Midge Forcipomyia taiwana (Diptera: Ceratopogonidae) and Nuage Localization of Vasa in Germline Cells. Insects, 11(2), 106. (SCI, 18/102, Entomology). MOST 105-2313-B-320-002.
  4. Chia-Yin Chiang, Yung-Hao Ching, Ting-Yan Chang, Liang-Shuan Hu, Yee Siang Yong, Pei Ying Keak, Ivana Mustika, Ming-Der Lin*, and Ben-Yang Liao* (2020, Jan). Novel Eye Genes Systematically Discovered through an Integrated Analysis of Mouse Transcriptomes and Phenome. Computational and Structural Biotechnology Journal, Volume 18, 2020, Pages 73-82. (SCI, 45/295, Biochemistry & Molecular Biology).
  5. Preethi Krishnaraj, Yu Chang, Tsung-Jung Ho, Nai-Chen Lu, Ming-Der Lin*, Hao-Ping Chen* (2019, Jan). In vivo pro-angiogenic effects of dracorhodin perchlorate in zebrafish embryos: A novel bioactivity evaluation platform for commercial dragon blood samples. Journal of food and drug analysis, Volume 27, Issue 1, January 2019, Pages 259-265. (SCI, 12/143, Food Science and Technology).

Full publication please see google scholar:
https://scholar.google.com.tw/citations?user=8zK3-LoAAAAJ&hl=zh-TW&oi=ao